G protein dependent alterations in [125I] iodocyanopindolol and ±cyanopindolol binding at 5HT1B binding sites in rat brain membranes
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چکیده
منابع مشابه
Binding of [125I]iodocyanopindolol by rat harderian gland crude membranes: kinetic characteristics and day-night variations.
The Harderian glands are innervated by sympathetic fibers originating in the superior cervical ganglia. The aim of this study is to characterize the beta-adrenergic receptors in the rat Harderian gland. The characteristics of beta-adrenergic receptors were determined in crude membrane preparations from rat Harderian gland, using [125I]iodocyanopindolol ([125I]CYP) as radioligand. The binding of...
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متن کاملCan [125I]-Iodocyanopindolol Label β3-Adrenoceptors in Rat Urinary Bladder?
β(3)-Adrenoceptors have been demonstrated to mediate urinary bladder smooth muscle relaxation but proof of their expression at the protein level has been missing because of lack of suitable antibodies or radioligands. As among various available radioligands [(125)I]-iodocyanopindolol ([(125)I]-ICYP) exhibited the smallest problems in labeling cloned human β(3)-adrenoceptors in previous studies,...
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ژورنال
عنوان ژورنال: Neurochemical Research
سال: 1989
ISSN: 0364-3190,1573-6903
DOI: 10.1007/bf00965517